HIV

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Chapter 36:  Anti-viral Agents

Viral Structure and Life Cycle
Implication for Chemotherapeutic Intervention

Rotavirus (left) 5 fold axis symmetry; Helical viral nucleocapsid (right) (Myxo- paramyxo-viruses)

Linda M. Stannard, 1995, used with permission

Wang, F and Kieff, E., Medical Virology, In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1065-1066.

Wang, F and Kieff, E., Medical Virology, In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1066-1068. 

 

Safrin, S. and Chambers, H. F Antiviral Agents, in Basic and Clinical Pharmacology,(Katzung, B. G., ed) Appleton-Lange, 1998, p. 788-801.
Hayden, F.G., Antimicrobial Agents: Antiviral Agents, In Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp.1191-1217
Wang, F and Kieff, E., Medical Virology, In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1065-1072.

 

 

Clinical Manifestations and Pharmacological Management of HIV

Table of Contents

Opportunistic Viral Infections

Neoplastic Disease

 

Antiviral Therapy for HIV Infected Patients

Fauci, A.S. and Lane, H.C., Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders:. In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1818-1852

 

Opportunistic Infection and Treatment 

(Check other materials for more current information)

Protozoal Infection

Toxoplasmosis

Protozoal Diarrhea

Fauci, A.S. and Lane, H.C., Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders:. In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1818-1852

Bacterial Infections

 

Mycobacterial Infections

Drugs to Treat Mycobacterial Infections

Fauci, A.S. and Lane, H.C., Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders:. In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1831-1835.

Tuberculosis

Isoniazid

 

Rifampin

 

Fungal Infections in HIV

Pneumocystis carinii Pneumonia

Candidiasis

Cryptococcosis

Histoplasmosis

Opportunistic Viral Infections

Ganciclovir

Foscarnet

Cidofovir

 

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Herpes Simplex Virus Infection

Varicella-Zoster Virus

 

Epstein-Barr Virus Infection

Other Herpes Viral Infections in Humans

Fauci, A.S. and Lane, H.C., Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders:. In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., andBraunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1831-1837.

 

Neoplasms in HIV

Introduction

Fauci, A.S. and Lane, H.C., Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders:. In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., andBraunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1837-1840.

Antiviral Treatment Strategies

 

Prophylaxis Against Secondary Infection

Fauci, A.S. and Lane, H.C., Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders:. In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., andBraunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1845-1854

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Antiviral Therapy for HIV Infected Patients

(MMWR 1998: 47 RR-3: 38-78)
From The Johns Hopkins Report,based on the recommendation of the Department of Health and Human Services/Kaiser Family Foundation as of April 1998] Updated information (http://www,hivatis.org and http://www.cdc.gov); Updated: "Drugs for HIV Infection", The Medical Letter, volume 42 (issue 1069), Jan. 10, 2000--check for more current information in this rapidly changing area:

Antiretroviral Treatment

Indication for Antiviral Treatment

Treatment Protocol (January, 2000)--check CDC for more current information

Drugs of choice for Adult HIV infection:

"Drugs for HIV Infection", The Medical Letter, volume 42 (issue 1069), Jan. 10, 2000, Published by The Medical Letter, Inc., 1000 Main Street, New Rochelle, New York, 10801; Fauci, A.S. and Lane, H.C., Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders:. In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, p. 1818-1852

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